MARC details
| 000 -LEADER |
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| fixed length control field |
02431nam a22002177a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
CHED |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250130143319.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250130e2018 ph ||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
Commission on Higher Education |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Villaverde, Eleanor Cuevas |
| 245 00 - TITLE STATEMENT |
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| Title |
Immunomodulatory activities of vaccinium myrtoides (Blume) miq. fruit |
| Remainder of title |
: lymphocytic proliferation and reactive oxygen species scavenging activity |
| Statement of responsibility, etc. |
/ Eleanor Cuevas Villaverde |
| 260 3# - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Los Baños |
| Name of publisher, distributor, etc. |
: University of the Philippines Los Baños |
| Date of publication, distribution, etc. |
,2018 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xxi, 145 leaves |
| Dimensions |
; 27 x 21cm. |
| 500 ## - GENERAL NOTE |
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| General note |
Thesis (Master of Science in Botany) -- University of the Philippines Los Baños, December 2018. |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
The increasing trend of healthier lifestyles plus the shift to preventive medicine has sparked the consumption of functional foods, such as blueberries, to improve the immune system. This study determined the phenolic, flavonoid, and antioxidant activity, and immunomodulatory properties of a native Philippine blueberry, Vaccinium myrtoides, through phytochemical and immune-based animal assays. Total phenolics (TP), total flavonoid (TF), and antioxidant activity (AOX) of the crude ethanolic blueberry extract (BBE) were tested through Folin-Ciocalteu, aluminum chloride, and DPPH assays, respectively, resulting to high amounts of each. In vitro immune-based assays showed significant activity of BBE on murine lymphocyte proliferation at 5g/mL BBE (p < 0.05) and ROS scavenging at 50 g/mL BBE (p < 0.05). In vivo experimentation of phosphate buffered saline (PBS)-, cyclophosphamide (CP)-, and immunosuppressed BBE (100 mg/kg and 400 mg/kg)- treated male ICR mice agreed with in vitro results of immunomodulation through lymphocyte proliferation (400 mg/kg BBE) and ROS scavenging (100 mg/kg BBE) but were not statistically significant (p > 0.05). Splenic weights increased with BBE treatment. Hepatoprotective nature of BBE ( I 00 mg/kg) against CP-induced toxicity was also noted. The results suggest that WV. myrtoides can possibly effect immunomodulation through lymphocyte proliferation and ROS scavenging. |
| 650 10 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Immunology |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://181.215.242.151/cgi-bin/koha/opac-retrieve-file.pl?id=4384746c677ce0b5856681294c26ee82">http://181.215.242.151/cgi-bin/koha/opac-retrieve-file.pl?id=4384746c677ce0b5856681294c26ee82</a> |
| Public note |
Abstract |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="http://181.215.242.151/cgi-bin/koha/opac-retrieve-file.pl?id=79f4a6c7171efdd2e307567a5f8c41ef">http://181.215.242.151/cgi-bin/koha/opac-retrieve-file.pl?id=79f4a6c7171efdd2e307567a5f8c41ef</a> |
| Public note |
Table of Contents |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
CHED Funded Research |
| Suppress in OPAC |
No |
